Amanda Chang
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Amanda Chang, MD
Internal Medicine Resident
I am one of the rising Chief Residents for the Iowa Internal Medicine residency program. I have a strong interest in clinical education, rural healthcare delivery, and artificial intelligence (AI) research. In particular, I am interested in how AI can be applied to cardiac imaging for diagnosis and prognosis, bridge healthcare gaps, and assist with medical education.
Education
MD, University of Iowa, Iowa City, IA
Licenses
MD, Iowa Board of Medicine
Selected Publications
Chang A, Suneja M. Polymyositis Masking Statin-Induced Necrotizing Autoimmune Myopathy: A Teachable Moment. JAMA Intern Med. 2025 Aug 18. doi: 10.1001/jamainternmed.2025.3862. Epub ahead of print. PMID: 40824649.
Chang A, Strom JB, Liu K. AI-Assisted Point-of-Care Ultrasound Networks-Considerations for Rural Health Care Delivery. JAMA Cardiol. 2025 Jul 1;10(7):643-644. doi: 10.1001/jamacardio.2025.0829. PMID: 40305012.
Chang A, Wu X, Liu K. Deep learning from latent spatiotemporal information of the heart: Identifying advanced bioimaging markers from echocardiograms. Biophys Rev (Melville). 2024 Mar 27;5(1):011304. doi: 10.1063/5.0176850. PMID: 38559589; PMCID: PMC10978053.
Zaman F, Isom N, Chang A, Wang YG, Abdelhamid A, Khan A, Makan M, Abdelghany M, Wu X, Liu K. Deep learning from atrioventricular plane displacement in patients with Takotsubo syndrome: lighting up the black-box. Eur Heart J Digit Health. 2023 Dec 6;5(2):134-143. doi: 10.1093/ehjdh/ztad077. PMID: 38505490; PMCID: PMC10944681.
Chang A, Khan A, Liu K. Correspondence on ‘Beta-blockers are associated with better long-term survival in patients with Takotsubo syndrome’ by Silverio et al. Heart Published Online First: 24 May 2022. doi: 10.1136/heartjnl-2022-321262
Lu, C.W., Wang, Y.G., Zaman, F., Wu, X., Adhaduk, M., Chang, A., Ji, J., Wei, T., Suksaranjit, P., Christodoulidis, G., Scalzetti, E., Feiglin, D., Liu, K., Predicting Adverse Cardiac Events in Sarcoidosis: Machine Learning from Automated Characterization of Regional Myocardial Remodeling, Int J Cardiovasc Imaging. 2022 Feb. Doi: 10.1007/s10554-022-02564-5.
Zaman, F., Ponnapureddy, R., Wang, Y.G., Chang, A., Cadaret, L.M., Abdelhamid, A., Roy, S.D., Makan, M., Zhou, R., Jayanna, M.B., Gnall, E., Dai, X., Singh, A., Zheng, J., Boppana, V.S., Wang, F., Singh, P., Wu, X., Liu, K. Spatio-temporal hybrid neural networks reduce erroneous human “judgement calls” in the diagnosis of Takotsubo syndrome. EClinicalMedicine. 2021 Sep 4;40:101115. Doi: 10.1016/j.eclinm.2021.101115.
Chang A., Wang Y.G., Jayanna M.B., Wu X., Cadaret L.M., Liu K. Mortality Correlates in Patients With Takotsubo Syndrome During the COVID-19 Pandemic. Mayo Clin Proc Innov Qual Outcomes. 2021 Dec;5(6):1050-1055. doi: 10.1016/j.mayocpiqo.2021.09.008. Epub 2021 Sep 29.
Chang, A., Cadaret, L.M. & Liu, K. Machine Learning in Electrocardiography and Echocardiography: Technological Advances in Clinical Cardiology. Curr Cardiol Rep 22, 161 (2020). https://doi.org/10.1007/s11886-020-01416-9
Chang, A., Stolin, G., Fan, J., Larreta, B. R., Fishbein, G. A., Wallace, W. D., Baas, A. S., Cruz, D., and Wang, J. (2019) Hypertrophic cardiomyopathy in a lupus patient: a case of hydroxychloroquine cardiotoxicity. ESC Heart Failure, 6: 1326– 1330. https://doi.org/10.1002/ehf2.12508.